systematic_review
    2013
    High Quality

    Combined and alternating paracetamol and ibuprofen therapy for febrile children

    Wong T, Stang AS, Ganshorn H, Hartling L, Maconochie IK, Thomsen AM, Johnson DW

    Published in Cochrane Database of Systematic Reviews

    Key Findings

    Combined or alternating antipyretics may lower temperature slightly more than monotherapy, but evidence for improved child comfort is weak and dosing errors are a risk.

    Conclusions

    Single-agent antipyretic dosing is adequate for most fevers.

    Limitations

    Small heterogeneous trials, mostly low quality.

    Related Health Concerns

    Fever

    Study Details

    Year:2013
    Quality Score:8/10

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    View on DOIView on PubMedOriginal Source

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