Dietary intake and biomarkers of alpha linolenic acid and risk of all cause, cardiovascular, and cancer mortality: systematic review and dose-response meta-analysis of cohort studies
Naghshi S, Aune D, Beyene J, Mobarak S, Asadi M, Sadeghi O
Published in BMJ
Methodology
Dose-response meta-analysis of prospective cohort studies of alpha-linolenic acid intake and biomarkers with mortality outcomes
Key Findings
Higher alpha-linolenic acid intake was associated with modestly lower all-cause and cardiovascular mortality but slightly higher cancer mortality
Conclusions
Plant omega-3 intake is associated with lower total mortality with an unexplained cancer signal
Limitations
Observational design; heterogeneity between dietary and biomarker measures
Supplements Studied
Higher alpha-linolenic acid intake was associated with modestly lower all-cause and cardiovascular mortality but slightly higher cancer mortality
Outcomes Measured
Higher alpha-linolenic acid intake was associated with modestly lower all-cause and cardiovascular mortality but slightly higher cancer mortality
Related Health Concerns
Study Details
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