Effect of omega-3 fatty acid supplementation on markers of inflammation and endothelial function in patients with chronic heart disease: A systematic review and meta-analysis
Ibrahim Mohialdeen Gubari M
Published in Cellular and Molecular Biology
Methodology
Systematic review and random/fixed-effects meta-analysis of 13 clinical trials of omega-3 fatty acid supplementation reporting inflammatory and endothelial function markers in chronic heart disease.
Key Findings
Pooled analysis indicated omega-3 supplementation significantly reduced circulating IL-6 and hs-CRP in patients with chronic heart disease.
Conclusions
Omega-3 fatty acids reduce inflammatory markers in chronic heart disease populations.
Limitations
Wide confidence intervals and heterogeneity across trials, disease-specific population, surrogate biomarker endpoints only.
Supplements Studied
Omega-3 FA supplementation significantly reduced the level of circulating IL-6.
Outcomes Measured
Omega-3 FA supplementation significantly reduced the level of circulating IL-6.
Study Details
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Disclosures
Funding
Not reported
This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.