meta_analysis
2022
High Quality
Ivy leaves extract EA 575 in the treatment of cough during acute respiratory tract infections: meta-analysis of double-blind, randomized, placebo-controlled trials
Völp A, Schmitz J, Bulitta M, Raskopf E, Acikel C
Published in Scientific Reports
Methodology
Individual patient data meta-analysis of two double-blind randomized placebo-controlled trials of ivy leaf dry extract EA 575 for 7 days
Key Findings
Bronchitis Severity Score fell more with EA 575 than placebo (8.6 vs 6.2) and more patients were cough-free at follow-up (56.2% vs 25.6%); adverse events were comparable
Conclusions
Ivy leaf extract EA 575 accelerates recovery from acute cough
Limitations
Only two trials of a single proprietary extract, manufacturer-sponsored, acute infection setting
Related Health Concerns
Study Details
Year:2022
Sample Size:390
Duration:2 weeks
Quality Score:7/10
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Disclosures
Funding
Engelhard Arzneimittel
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