meta_analysis
    2022
    High Quality

    Ivy leaves extract EA 575 in the treatment of cough during acute respiratory tract infections: meta-analysis of double-blind, randomized, placebo-controlled trials

    Völp A, Schmitz J, Bulitta M, Raskopf E, Acikel C

    Published in Scientific Reports

    Methodology

    Individual patient data meta-analysis of two double-blind randomized placebo-controlled trials of ivy leaf dry extract EA 575 for 7 days

    Key Findings

    Bronchitis Severity Score fell more with EA 575 than placebo (8.6 vs 6.2) and more patients were cough-free at follow-up (56.2% vs 25.6%); adverse events were comparable

    Conclusions

    Ivy leaf extract EA 575 accelerates recovery from acute cough

    Limitations

    Only two trials of a single proprietary extract, manufacturer-sponsored, acute infection setting

    Related Health Concerns

    Study Details

    Year:2022
    Sample Size:390
    Duration:2 weeks
    Quality Score:7/10

    Disclosures

    Funding

    Engelhard Arzneimittel

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