systematic_review
    2017
    High Quality

    Alginate therapy is effective treatment for gastroesophageal reflux disease symptoms: a systematic review and meta-analysis

    Leiman DA, Riff BP, Morgan S, Metz DC, Falk GW, Lewis JD

    Published in Diseases of the Esophagus

    Methodology

    Systematic review and meta-analysis of RCTs comparing alginate-based formulations with placebo or antacids in GERD and non-erosive reflux disease

    Key Findings

    Alginate therapy was more effective than placebo and comparable or superior to antacids for heartburn and other GERD symptoms

    Conclusions

    Alginate is an effective, well-tolerated option for GERD symptom relief

    Limitations

    Heterogeneity in outcomes and formulations; many small older trials; limited objective endpoints

    Related Health Concerns

    GERD

    Study Details

    Year:2017
    Quality Score:8/10

    Access Study

    View on DOIView on PubMedOriginal Source

    Disclosures

    Funding

    Academic institutional support

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