meta_analysis
    2022

    Efficacy of Tongkat Ali (Eurycoma longifolia) on erectile function improvement: systematic review and meta-analysis of randomized controlled trials

    Leisegang K, Sengupta P, Agarwal A, Henkel R

    Published in Complementary Therapies in Medicine

    Abstract

    Systematic review and meta-analysis of randomized trials demonstrating tongkat ali significantly improves erectile function, with evidence of increased testosterone levels and improved libido across multiple studies.

    Methodology

    Systematic review and meta-analysis of randomised placebo-controlled trials of Eurycoma longifolia extract reporting erectile function or related sexual health outcomes.

    Key Findings

    Pooled analysis of randomised trials of Eurycoma longifolia (Tongkat Ali) found small improvements in erectile function scores and some testosterone-related parameters versus placebo, but effects were inconsistent across trials and largely limited to men with baseline hypogonadism or stress-related low testosterone.

    Conclusions

    Tongkat Ali shows a modest, low-certainty signal for erectile function; current trials are too small and heterogeneous to recommend it as a treatment for erectile dysfunction.

    Limitations

    Few eligible RCTs with small samples, variable extract standardisation and dosing, short durations, mixed populations, and several industry-funded studies with high risk of bias.

    Supplements Studied

    Pooled analysis of randomised trials of Eurycoma longifolia (Tongkat Ali) found small improvements in erectile function scores and some testosterone-related parameters versus placebo, but effects were inconsistent across trials and largely limited to men with baseline hypogonadism or stress-related low testosterone.

    Outcomes Measured

    Systematic review and meta-analysis demonstrating tongkat ali significantly improves erectile function, with evidence of increased testosterone levels and improved libido across multiple studies.

    Pooled analysis of randomised trials of Eurycoma longifolia (Tongkat Ali) found small improvements in erectile function scores and some testosterone-related parameters versus placebo, but effects were inconsistent across trials and largely limited to men with baseline hypogonadism or stress-related low testosterone.

    Study Details

    Year:2022
    Quality Score:6/10

    Disclosures

    Funding

    Academic institutional funding

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