meta_analysis
    2025

    Protective effect of Astragalus polysaccharide on diabetic nephropathy: a systematic review and meta-analysis reveals the efficacy and potential mechanisms

    He Y, Zhao WJ, Yang ZC, Qin MM

    Published in Biomedical Reports

    Key Findings

    Astragalus polysaccharide improved proteinuria and renal function markers in preclinical and clinical diabetic nephropathy models, with mechanisms linked to oxidative stress and inflammation pathways.

    Conclusions

    Astragalus polysaccharide shows consistent renoprotective signals that require rigorous human confirmation.

    Limitations

    Heavy reliance on animal studies and low-quality clinical trials; publication bias likely.

    Supplements Studied

    Astragalus polysaccharide improved proteinuria and renal function markers, with mechanisms linked to oxidative stress and inflammation pathways.

    Study Details

    Year:2025
    Quality Score:5/10

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