Effects of Nigella sativa on glycemic control, lipid profiles, and biomarkers of inflammatory and oxidative stress: A systematic review and meta-analysis of randomized controlled clinical trials
Hallajzadeh J, Milajerdi A, Mobini M, et al.
Published in Phytotherapy Research
Abstract
Systematic review and meta-analysis of Nigella sativa effects on glycemic and lipid markers and oxidative stress.
Key Findings
Nigella sativa significantly reduced fasting glucose, HbA1c, total cholesterol and LDL cholesterol, while effects on HDL and inflammatory markers were inconsistent.
Conclusions
Black seed shows metabolic benefits, but heterogeneity across trials is high.
Limitations
Mostly small trials from limited geographic regions; variable formulations.
Supplements Studied
Nigella sativa significantly reduced fasting glucose, HbA1c, total cholesterol and LDL cholesterol, while effects on HDL and inflammatory markers were inconsistent.
Outcomes Measured
Nigella sativa significantly reduced fasting glucose, HbA1c, total cholesterol and LDL cholesterol, while effects on HDL and inflammatory markers were inconsistent.
Nigella sativa significantly reduced fasting glucose, HbA1c, total cholesterol and LDL cholesterol, while effects on HDL and inflammatory markers were inconsistent.
Related Health Concerns
Study Details
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