observational
    2012

    Palmitoylethanolamide in the Treatment of Chronic Pain Caused by Different Etiopathogenesis

    Gatti A, Lazzari M, Gianfelice V, Di Paolo A, Sabato E, Sabato AF

    Published in Pain Medicine

    Methodology

    Multicenter observational study of PEA added to standard analgesic therapy in patients with chronic pain of varied etiology

    Key Findings

    Pain intensity decreased significantly from baseline during PEA add-on therapy across neuropathic, mixed and nociceptive pain groups

    Conclusions

    Add-on PEA was associated with clinically meaningful reductions in pain intensity across pain etiologies

    Limitations

    Open-label design without placebo control limits causal inference

    Supplements Studied

    PEA
    Compound

    Pain intensity decreased significantly from baseline during PEA add-on therapy across neuropathic, mixed and nociceptive pain groups

    Outcomes Measured

    Pain intensity decreased significantly from baseline during PEA add-on therapy across neuropathic, mixed and nociceptive pain groups

    Related Health Concerns

    Study Details

    Year:2012
    Sample Size:610
    Duration:3 weeks
    Quality Score:5/10

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