rct
    1997
    High Quality

    Does Dong Quai Have Estrogenic Effects in Postmenopausal Women? A Double-Blind, Placebo-Controlled Trial

    Hirata JD, Swiersz LM, Zell B, Small R, Ettinger B

    Published in Fertility and Sterility

    Methodology

    Twenty-four-week double-blind placebo-controlled RCT of dong quai 4.5 g/day in 71 postmenopausal women, assessing hot flushes, endometrial thickness and vaginal maturation.

    Key Findings

    Dong quai produced no significant difference from placebo in hot flush frequency, endometrial thickness or vaginal cell maturation.

    Conclusions

    Dong quai used alone showed no oestrogenic activity or benefit for menopausal hot flushes.

    Limitations

    Single herb, single dose; moderate sample; may not apply to traditional multi-herb formulas.

    Supplements Studied

    Dong quai produced no significant difference from placebo in hot flush frequency, endometrial thickness or vaginal cell maturation.

    Outcomes Measured

    Dong quai produced no significant difference from placebo in hot flush frequency.

    Related Health Concerns

    Study Details

    Year:1997
    Sample Size:71
    Duration:24 weeks
    Quality Score:8/10

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