rct
2014
High Quality
Effect of melatonin on incidence of delirium among patients with hip fracture: a multicentre, double-blind randomized controlled trial
de Jonghe A, van Munster BC, Goslings JC
Published in CMAJ
Methodology
Multicentre double-blind RCT of melatonin 3 mg versus placebo for 5 days after hip fracture.
Key Findings
Melatonin did not reduce delirium incidence compared with placebo.
Conclusions
Melatonin failed to prevent postoperative confusion in a large well-designed trial.
Limitations
Single dose regimen; surgical population only.
Supplements Studied
Melatonin
Compound
Melatonin did not reduce delirium incidence compared with placebo.
Related Health Concerns
Study Details
Year:2014
Sample Size:452
Quality Score:8/10
Access Study
This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.