meta_analysis
    2021
    High Quality

    Ursodeoxycholic acid in intrahepatic cholestasis of pregnancy: a systematic review and individual participant data meta-analysis

    Unknown authors

    Published in Lancet Gastroenterol Hepatol

    Key Findings

    Ursodeoxycholic acid reduced pruritus and bile acid levels but did not reduce adverse perinatal outcomes overall.

    Conclusions

    Biochemical improvement without clinical outcome benefit.

    Outcomes Measured

    Bile Flow Enhancement
    Primary

    Ursodeoxycholic acid reduced pruritus and bile acid levels but did not reduce adverse perinatal outcomes overall.

    Study Details

    Year:2021
    Quality Score:9/10

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