rct
    2021
    High Quality

    Exercise training and burdock root (Arctium lappa L.) extract independently improve abdominal obesity and sex hormones in elderly women with metabolic syndrome

    Ha MS, Yook JS, Lee M, Suwabe K, Jeong WM

    Published in Scientific Reports

    Methodology

    Randomized, double-blind controlled trial of aquatic exercise and/or burdock root extract in elderly women with metabolic syndrome; body composition and serum sex hormones (testosterone, estradiol, SHBG, DHEA-S) assessed.

    Key Findings

    SHBG and estradiol rose with both aquatic exercise and burdock extract; DHEA-S increased only in the burdock group; the combined intervention produced no synergistic or additive benefit on any sex-hormone outcome.

    Conclusions

    Burdock root extract independently improved selected sex-hormone and body-composition markers, but added nothing when combined with exercise.

    Limitations

    Small groups, older women with metabolic syndrome only, hormone surrogates rather than clinical endpoints, no synergy observed.

    Supplements Studied

    SHBG and estradiol levels were enhanced by both AE and BE and correlated with changes in fat-related body composition.

    Outcomes Measured

    SHBG and estradiol levels were enhanced by both AE and BE and correlated with changes in fat-related body composition.

    Related Health Concerns

    Study Details

    Year:2021
    Duration:16 weeks
    Quality Score:7/10

    Disclosures

    Funding

    Not clearly stated

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