Efficacy of topical agents for prevention of postoperative sore throat after single lumen tracheal intubation: a Bayesian network meta-analysis
Singh NP, Makkar JK, Cappellani RB, Sinha A, Lakshminarasimhachar A
Published in Canadian Journal of Anaesthesia
Methodology
Bayesian network meta-analysis of 70 randomized controlled trials comparing 11 topical agents for prevention of postoperative sore throat
Key Findings
Magnesium (OR 0.10) and liquorice ranked among the most effective topical agents for reducing sore throat at 24 hours versus control
Conclusions
Liquorice gargle is among the better-supported topical options for throat irritation after intubation
Limitations
Indirect comparisons, heterogeneous dosing and delivery, surgical population only
Supplements Studied
Bayesian NMA showed that magnesium (odds ratio [OR], 0.10; 95% credible interval [CrI], 0.03 to 0.26), liquorice
Related Health Concerns
Study Details
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