The impact of six-week dihydrogen-pyrroloquinoline quinone supplementation on mitochondrial biomarkers, brain metabolism, and cognition in elderly individuals with mild cognitive impairment: a randomized controlled trial

Ostojic SM

Published in The Journal of Nutrition, Health and Aging

Key Findings

Six weeks of hydrogen-PQQ altered brain metabolite ratios and some mitochondrial biomarkers, with limited change in cognitive test scores.

Biomarker signals were seen without clear cognitive improvement over six weeks.

Very short duration, small sample, combined intervention.

Compound

Six weeks of hydrogen-PQQ altered brain metabolite ratios and some mitochondrial biomarkers, with limited change in cognitive test scores.

Year:2024

Sample Size:24

Duration:6 weeks

Quality Score:5/10

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