rct
2010
High Quality
Treatment of moderate to severe premenstrual syndrome with Vitex agnus castus (BNO 1095) in Chinese women
Ma L, Lin S, Chen R, Zhang Y, Chen F, Wang X
Published in Gynecological Endocrinology
Methodology
Randomised, double-blind, placebo-controlled trial of Vitex agnus castus BNO 1095 over three menstrual cycles in 217 Chinese women with moderate to severe premenstrual syndrome.
Key Findings
Premenstrual syndrome diary scores fell significantly more with Vitex than placebo across all three cycles.
Conclusions
Vitex agnus castus reduced premenstrual symptom severity in this population.
Limitations
Manufacturer-sponsored, symptom-diary endpoints, three-cycle duration.
Supplements Studied
Premenstrual syndrome diary scores fell significantly more with Vitex than placebo across three cycles.
Related Health Concerns
Study Details
Year:2010
Sample Size:217
Duration:12 weeks
Quality Score:7/10
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