crossover
    2019

    Bifidobacterium longum 1714 modulates brain activity and stress responses in healthy volunteers: neuroimaging evidence

    Wang H, Braun C, Murphy EF, Enck P

    Published in American Journal of Gastroenterology

    Abstract

    Randomised crossover neuroimaging study of Bifidobacterium longum 1714 in healthy volunteers.

    Key Findings

    B. longum 1714 altered resting-state neural oscillations and reduced subjective stress during social stress testing, without changing gut symptoms.

    Conclusions

    Neurophysiological effects are demonstrable but clinical relevance remains unproven.

    Limitations

    Small healthy-volunteer crossover; surrogate neuroimaging endpoints.

    Supplements Studied

    B. longum 1714 altered resting-state neural oscillations and reduced subjective stress during social stress testing, without changing gut symptoms.

    Outcomes Measured

    B. longum 1714 altered resting-state neural oscillations and reduced subjective stress during social stress testing, without changing gut symptoms.

    Study Details

    Year:2019
    Sample Size:40
    Duration:4 weeks
    Quality Score:6/10

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