Treatment of vasomotor symptoms of menopause with black cohosh, multibotanicals, soy, hormone therapy, or placebo: a randomized trial
Newton KM, Reed SD, LaCroix AZ, Grothaus LC, Ehrlich K, Guiltinan J
Published in Annals of Internal Medicine
Abstract
Randomized, double-blind, placebo-controlled trial comparing black cohosh, multibotanicals, soy, hormone therapy and placebo for vasomotor symptoms.
Key Findings
Black cohosh, multibotanical preparations and soy did not reduce vasomotor symptom frequency or intensity more than placebo at any timepoint, whereas hormone therapy did.
Conclusions
This well-powered trial found no benefit of black cohosh for hot flashes.
Limitations
Single population, symptom-diary endpoints, botanical preparations may differ from other products.
Supplements Studied
Black cohosh, multibotanical preparations and soy did not reduce vasomotor symptom frequency or intensity more than placebo at any timepoint, whereas hormone therapy did.
Outcomes Measured
Black cohosh, multibotanical preparations and soy did not reduce vasomotor symptom frequency or intensity more than placebo at any timepoint, whereas hormone therapy did.
Related Health Concerns
Study Details
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