cohort
2012
Dietary silicon interacts with oestrogen to influence bone health: evidence from the Aberdeen Prospective Osteoporosis Screening Study
Macdonald HM, Hardcastle AC, Jugdaohsingh R, Fraser WD, Reid DM, Powell JJ
Published in Bone
Methodology
Prospective cohort of 3,198 women examining dietary silicon intake and change in femoral neck and lumbar spine BMD.
Key Findings
No overall association between silicon intake and BMD; a positive association appeared only in oestrogen-replete women.
Conclusions
Any skeletal benefit of dietary silicon appears conditional on oestrogen status rather than general.
Limitations
Observational; food-frequency estimates of silicon intake are imprecise.
Supplements Studied
Silica
Mineral
No overall association between silicon intake and BMD; a positive association appeared only in oestrogen-replete women.
Related Health Concerns
Study Details
Year:2012
Sample Size:3,198
Quality Score:6/10
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