meta_analysis
    2018
    High Quality

    Alpha-lipoic acid supplementation and leptin concentrations: a meta-analysis of randomized controlled trials

    Namazi N, Larijani B, Azadbakht L

    Published in Clinical Nutrition

    Methodology

    Meta-analysis of randomized trials of alpha-lipoic acid reporting leptin and adiponectin concentrations.

    Key Findings

    Alpha-lipoic acid significantly reduced circulating leptin alongside modest weight reduction.

    Conclusions

    Alpha-lipoic acid lowers leptin concentrations, consistent with improved energy-balance signalling.

    Limitations

    Short trial durations; most trials in metabolic disease populations.

    Supplements Studied

    Alpha-lipoic acid significantly reduced circulating leptin alongside modest weight reduction

    Outcomes Measured

    Leptin Sensitivity

    Alpha-lipoic acid significantly reduced circulating leptin alongside modest weight reduction

    Study Details

    Year:2018
    Duration:12 weeks
    Quality Score:7/10

    Access Study

    View on DOIView on PubMedOriginal Source

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