Polypodium leucotomos extract and photoprotection: systematic review of clinical evidence
Parrado C, Mascaraque M, Gilaberte Y, Juarranz A, Gonzalez S
Published in International Journal of Molecular Sciences
Methodology
Review of in vitro, animal and human trials of oral Polypodium leucotomos extract on UV-induced erythema and DNA damage.
Key Findings
Oral Polypodium leucotomos raised the minimal erythema dose and reduced UV-induced DNA damage and sunburn cell formation in human trials.
Conclusions
Oral fern extract provides modest systemic photoprotection as an adjunct to sunscreen.
Limitations
Small trials; not a sunscreen replacement.
Outcomes Measured
Oral Polypodium leucotomos raised the minimal erythema dose and reduced UV-induced DNA damage and sunburn cell formation
Study Details
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