Diamine oxidase (DAO) supplement reduces headache in episodic migraine patients with DAO deficiency: A randomized double-blind trial
Izquierdo-Casas J, Comas-Baste O
Published in Clinical Nutrition
Methodology
Randomized double-blind placebo-controlled trial of oral diamine oxidase supplementation in episodic migraine patients with DAO deficiency.
Key Findings
Headache duration was significantly shorter with DAO supplementation than placebo; attack frequency did not differ significantly.
Conclusions
Supplemental DAO may shorten migraine attacks in people with low DAO activity, without reducing attack frequency.
Limitations
Small sample, selected DAO-deficient population, mixed endpoint results.
Outcomes Measured
Headache duration was significantly shorter with diamine oxidase supplementation than placebo in DAO-deficient migraine patients
Study Details
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