meta_analysis
    2019
    High Quality

    Vitamin D to prevent exacerbations of COPD: systematic review and meta-analysis of individual participant data

    Jolliffe DA, Greenberg L, Hooper RL

    Published in Thorax

    Methodology

    Individual participant data meta-analysis of RCTs of vitamin D in COPD.

    Key Findings

    Vitamin D reduced moderate-to-severe exacerbation rates in participants with baseline 25(OH)D below 25 nmol/L, but not in those with higher levels.

    Conclusions

    Vitamin D helps chronic bronchitis exacerbations only in deficiency.

    Limitations

    Small number of trials; subgroup-driven finding.

    Supplements Studied

    Vitamin D
    Vitamin

    Vitamin D reduced moderate-to-severe exacerbation rates in participants with baseline 25(OH)D below 25 nmol/L.

    Outcomes Measured

    Respiratory Health

    Vitamin D reduced moderate-to-severe exacerbation rates in participants with baseline 25(OH)D below 25 nmol/L.

    Related Health Concerns

    Chronic Bronchitis
    Shortness of Breath

    Study Details

    Year:2019
    Sample Size:469
    Quality Score:8/10

    Access Study

    View on DOIView on PubMedOriginal Source

    This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.