systematic_review
    2022
    High Quality

    Vitamin and mineral supplements for the primary prevention of cardiovascular disease and cancer: US Preventive Services Task Force review

    O'Connor EA, Evans CV, Ivlev I, Rushkin MC, Thomas RG, Martin A

    Published in JAMA

    Methodology

    Evidence review of 84 studies of vitamin, mineral and multivitamin supplementation for primary prevention of cardiovascular disease, cancer and mortality.

    Key Findings

    No consistent benefit was found for multivitamins or most single nutrients; beta-carotene increased lung cancer risk in high-risk groups.

    Conclusions

    Routine supplementation for disease prevention is not supported in well-nourished adults.

    Limitations

    Generalisability limited for deficient populations; heterogeneous nutrient doses.

    Supplements Studied

    No consistent benefit was found for multivitamins or most single nutrients

    No consistent benefit was found for multivitamins or most single nutrients; beta-carotene increased lung cancer risk in high-risk groups.

    Related Health Concerns

    Study Details

    Year:2022
    Sample Size:739,803
    Duration:260 weeks
    Quality Score:9/10

    This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.