A placebo-controlled, double-blind trial of Ginkgo biloba for antidepressant-induced sexual dysfunction
Kang BJ, Lee SJ, Kim MD, Cho MJ
Published in Human Psychopharmacology
Methodology
Randomized, double-blind, placebo-controlled trial of Ginkgo biloba versus placebo for two months in patients with antidepressant-induced sexual dysfunction
Key Findings
No statistically significant difference from placebo at weeks 2, 4 or 8. Both groups improved from baseline, highlighting a large placebo response in sexual function outcomes.
Conclusions
Ginkgo biloba did not replicate earlier positive findings and performed no better than placebo for antidepressant-induced sexual dysfunction.
Limitations
Very small sample (n = 37), short duration, single-centre
Supplements Studied
This study did not replicate a prior positive finding supporting the use of Ginkgo biloba for antidepressant, especially SSRI, induced sexual dysfunction
Outcomes Measured
This study did not replicate a prior positive finding supporting the use of Ginkgo biloba for antidepressant, especially SSRI, induced sexual dysfunction
Study Details
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