cohort
2004
High Quality
The Beta-Carotene and Retinol Efficacy Trial: Incidence of Lung Cancer and Cardiovascular Disease Mortality During 6-Year Follow-up After Stopping Beta-Carotene and Retinol Supplements
Goodman GE, Thornquist MD, Balmes J, et al.
Published in Journal of the National Cancer Institute
Abstract
Six-year post-intervention follow-up of the CARET randomized trial.
Key Findings
Excess lung cancer risk in the supplement arm diminished after supplementation stopped, though risks remained elevated among women.
Conclusions
The harm from beta carotene appears largely reversible after discontinuation.
Limitations
Post-intervention observational follow-up; no continuing randomized comparison.
Supplements Studied
Beta-Carotene
Compound
Excess lung cancer risk in the supplement arm diminished after supplementation stopped, though risks remained elevated among women.
Related Health Concerns
Study Details
Year:2004
Sample Size:18,314
Quality Score:7/10
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This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.