systematic_review
    2019
    High Quality

    Antioxidants for male subfertility

    Smits RM, Mackenzie-Proctor R, Yazdani A, Stankiewicz MT, Jordan V, Showell MG

    Published in Cochrane Database of Systematic Reviews

    Methodology

    Cochrane review of 61 randomised trials of antioxidant supplementation in subfertile men measuring live birth, pregnancy and semen parameters.

    Key Findings

    Antioxidants may improve live birth and clinical pregnancy rates in subfertile men, but the evidence was of low certainty and driven by small trials.

    Conclusions

    Antioxidant supplementation plausibly improves sperm outcomes with low certainty.

    Limitations

    Low quality evidence; heterogeneous antioxidant regimens.

    Outcomes Measured

    Sperm Quality
    Primary

    Antioxidants may improve live birth and clinical pregnancy rates in subfertile men, but the evidence was of low certainty

    Study Details

    Year:2019
    Sample Size:6,264
    Duration:26 weeks
    Quality Score:8/10

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    View on DOIView on PubMedOriginal Source

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