Nutritional Interventions in Adult Patients With Irritable Bowel Syndrome: An Umbrella Review of Systematic Reviews and Meta-analyses of Randomized Clinical Trials
Zeraattalab-Motlagh S, Ranjbar M, Mohammadi H, Adibi P
Published in Nutrition Reviews
Methodology
Umbrella review of 58 meta-analyses covering 175 randomized trials of 11 nutritional interventions in adults with IBS, with effect sizes recalculated under random-effects models and certainty graded with GRADE.
Key Findings
Soluble fiber, peppermint oil and aloe vera improved IBS symptoms; vitamin D3 and curcumin improved symptom severity, but overall certainty of evidence was low.
Conclusions
Several supplements modestly reduce IBS-related abdominal pain, but evidence certainty is generally low.
Limitations
Low GRADE certainty across most comparisons; heterogeneity between the pooled meta-analyses.
Supplements Studied
soluble fiber, peppermint oil, and aloe vera improved IBS symptoms, and vitamin D3 and curcumin improved IBS symptom severity
soluble fiber, peppermint oil, and aloe vera improved IBS symptoms, and vitamin D3 and curcumin improved IBS symptom severity
soluble fiber, peppermint oil, and aloe vera improved IBS symptoms, and vitamin D3 and curcumin improved IBS symptom severity
Related Health Concerns
Study Details
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Disclosures
Funding
Not reported
This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.