systematic_review
    2019
    High Quality

    Best practices in mitigating the risk of biotin interference with laboratory testing

    Bowen R, Benavides R, Colon-Franco JM, et al.

    Published in Clinical Biochemistry

    Abstract

    Consensus guidance on identifying and mitigating biotin interference in laboratory testing.

    Key Findings

    Dietary biotin intake rarely reaches interference thresholds, but supplements of 5 mg or more can produce clinically significant assay interference.

    Conclusions

    Risk is dose-dependent; typical dietary intake is not a concern.

    Limitations

    Expert consensus and analytical data rather than clinical outcome trials.

    Supplements Studied

    Dietary biotin intake rarely reaches interference thresholds, but supplements of 5 mg or more can produce clinically significant assay interference.

    Study Details

    Year:2019
    Quality Score:7/10

    This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.