observational
2004
Indole-3-carbinol for recurrent respiratory papillomatosis: long-term results
Rosen CA, Bryson PC
Published in Journal of Voice
Methodology
Prospective open-label long-term follow-up of indole-3-carbinol treatment in patients with recurrent respiratory papillomatosis
Key Findings
About one third of patients had cessation of papilloma growth and another third had reduced growth rate, while the remainder showed no clinical response.
Conclusions
Indole-3-carbinol produced partial responses in recurrent respiratory papillomatosis in an uncontrolled series.
Limitations
Open-label, no control group, variable follow-up.
Supplements Studied
Indole-3-Carbinol
Compound
About one third of patients had cessation of papilloma growth and another third had reduced growth rate.
Study Details
Year:2004
Sample Size:33
Duration:260 weeks
Quality Score:4/10
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