A randomized, double-blind, placebo-controlled, multicenter study of a ginger extract in the management of chemotherapy-induced nausea and vomiting in patients receiving high-dose cisplatin
Bossi P, Cortinovis D, Fatigoni S, Cossu Rocca M, Fabi A, Seminara P, Ripamonti C, Alfieri S, Granata R, Bergamini C, Agustoni F, Bidoli P, Nolè F, Pessi MA, Macchi F, Michellini L, Montanaro F, Roila F
Published in Annals of Oncology
Methodology
Randomized, double-blind, placebo-controlled multicenter trial of standardized ginger extract added to guideline antiemetic prophylaxis in patients receiving high-dose cisplatin.
Key Findings
Adding ginger to standard antiemetic prophylaxis did not reduce the incidence or severity of delayed chemotherapy-induced nausea and vomiting compared with placebo.
Conclusions
Ginger provides no additional benefit over modern guideline antiemetic regimens in high-dose cisplatin chemotherapy.
Limitations
Only tested as an add-on to strong antiemetics; single extract and dose.
Supplements Studied
Adding ginger to standard antiemetic prophylaxis did not reduce delayed chemotherapy-induced nausea and vomiting compared with placebo.
Related Health Concerns
Study Details
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Disclosures
Funding
Academic/hospital funding with extract supplied by manufacturer
This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.