Vitex agnus-castus in premenstrual syndrome: a meta-analysis of double-blind randomised controlled trials
Csupor D, Lantos T, Hegyi P, Benkő R, Viola R, Gyöngyi Z, Csécsei P, Tóth B, Vasas A
Published in Complementary Therapies in Medicine
Methodology
Meta-analysis restricted to double-blind randomised controlled trials of Vitex agnus-castus for premenstrual syndrome, assessing methodological quality.
Key Findings
Vitex was more effective than placebo, but most trials had methodological shortcomings and the certainty of evidence was rated low.
Conclusions
Available evidence favours Vitex for premenstrual syndrome while highlighting substantial methodological limitations.
Limitations
Small number of high-quality trials; industry sponsorship common.
Supplements Studied
Vitex was more effective than placebo, though most trials had methodological shortcomings and low certainty.
Related Health Concerns
Study Details
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