Momordica charantia Administration Improves Insulin Secretion in Type 2 Diabetes Mellitus
Cortez-Navarrete M, Martínez-Abundis E, Pérez-Rubio KG, González-Ortiz M, Méndez-Del Villar M
Published in Journal of Medicinal Food
Methodology
Randomized, double-blind, placebo-controlled trial of 2000 mg/day Momordica charantia for 3 months in drug-naive type 2 diabetes with OGTT-derived indices.
Key Findings
Significant decreases in weight, BMI, body fat, waist circumference, HbA1c, 2-hour glucose and glucose AUC; significant increase in insulin AUC.
Conclusions
Bitter melon improved insulin secretion and several glycemic measures in untreated type 2 diabetes.
Limitations
Very small pilot sample, short duration, single centre.
Supplements Studied
A significant increase in insulin AUC (56,562 ± 36,078 vs. 65,256 ± 42,720 pmol/L/min, P = .043)
Outcomes Measured
significant decreases in weight, body mass index (BMI), fat percentage, waist circumference (WC), glycated hemoglobin A1c (A1C), 2-h glucose in OGTT, and AUC of glucose
Related Health Concerns
Study Details
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Disclosures
Funding
Not reported
This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.