rct
    2005
    High Quality

    Effect of multivitamin and mineral supplementation on immune function in the elderly: a randomized trial

    Avenell A, Campbell MK, Cook JA, Hannaford PC, Kilonzo MM, McNeill G, Milne AC, Ramsay CR, Seymour DG, Stephen AI, Vale LD

    Published in BMJ

    Methodology

    Large randomized double-blind placebo-controlled trial of daily multivitamin and mineral supplementation in adults aged 65 and over, measuring infection-related contacts and hospitalisation.

    Key Findings

    Multivitamin and mineral supplementation did not reduce infection rates, days of infection or primary care contacts compared with placebo.

    Conclusions

    Well-designed null trial: routine multivitamins do not improve immune outcomes in the elderly.

    Limitations

    Community-dwelling, largely nutrient-replete population.

    Supplements Studied

    Multivitamin and mineral supplementation did not reduce infection rates, days of infection or primary care contacts compared with placebo

    Outcomes Measured

    Multivitamin and mineral supplementation did not reduce infection rates, days of infection or primary care contacts compared with placebo

    Multivitamin and mineral supplementation did not reduce infection rates or days of infection compared with placebo

    Multivitamin and mineral supplementation did not reduce infection rates, days of infection or primary care contacts compared with placebo.

    Study Details

    Year:2005
    Sample Size:910
    Duration:52 weeks
    Quality Score:9/10

    This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.