rct
    2020
    High Quality

    Momordica charantia for type 2 diabetes mellitus: hypoglycemic efficacy and safety in patients with type 2 diabetes mellitus

    Kim SK, Jung J, Jung JH, Yoon N, Kang SS

    Published in Complementary Therapies in Medicine

    Methodology

    Randomized, placebo-controlled trial of bitter melon extract as adjuvant therapy over 12 weeks.

    Key Findings

    HbA1c was unchanged versus placebo; mean fasting glucose fell in the bitter melon group (p = 0.014). No serious adverse events.

    Conclusions

    Bitter melon extract lowered fasting glucose but did not change HbA1c over 12 weeks.

    Limitations

    Single centre, modest sample, no HbA1c benefit despite fasting glucose change.

    Supplements Studied

    After treatment with bitter melon extract for 12 weeks, the HbA1c levels of the bitter melon and placebo groups remained unchanged; however, the average fasting glucose level of the bitter melon group decreased (p = 0.014).

    Outcomes Measured

    the average fasting glucose level of the bitter melon group decreased (p = 0.014)

    Related Health Concerns

    Study Details

    Year:2020
    Sample Size:90
    Duration:12 weeks
    Quality Score:7/10

    Disclosures

    Funding

    Not reported

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