rct
    2010

    Pycnogenol treatment of acute hemorrhoidal episodes

    Belcaro G

    Published in Phytotherapy Research

    Methodology

    Randomized controlled study of oral Pycnogenol, oral plus topical Pycnogenol, or placebo over two weeks in patients with acute haemorrhoidal episodes, scoring bleeding, pain and signs of thrombosis.

    Key Findings

    Combined oral and topical Pycnogenol during acute haemorrhoidal episodes reduced bleeding, pain scores and episode duration compared with control, with the oral-plus-topical arm performing best.

    Conclusions

    Oral and topical Pycnogenol reduced symptoms of acute hemorrhoidal episodes.

    Limitations

    Small sample (n=84), short two-week follow-up, subjective symptom scoring, limited blinding of the topical arm, and author affiliation with the ingredient supplier.

    Supplements Studied

    Combined oral and topical Pycnogenol during acute haemorrhoidal episodes reduced bleeding, pain scores and episode duration compared with control, with the oral-plus-topical arm performing best.

    Related Health Concerns

    Study Details

    Year:2010
    Sample Size:84
    Duration:2 weeks
    Quality Score:5/10

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