rct
    2005
    High Quality

    Strontium ranelate reduces the risk of nonvertebral fractures in postmenopausal women with osteoporosis: Treatment of Peripheral Osteoporosis (TROPOS) study

    Reginster JY, Seeman E, De Vernejoul MC, Adami S, Compston J, Phenekos C, Devogelaer JP, Curiel MD, Sawicki A, Goemaere S, Sorensen OH, Felsenberg D, Meunier PJ

    Published in Journal of Clinical Endocrinology and Metabolism

    Methodology

    TROPOS: 3-year randomized, double-blind, placebo-controlled trial of strontium ranelate in 5,091 postmenopausal women at risk of peripheral fracture.

    Key Findings

    Nonvertebral fracture risk fell by 16%, and hip fracture risk by 36% in the high-risk subgroup.

    Conclusions

    Strontium ranelate reduces nonvertebral fracture risk in postmenopausal osteoporosis.

    Limitations

    Hip fracture benefit was a post hoc high-risk subgroup finding; industry sponsored.

    Supplements Studied

    Strontium
    Mineral

    Strontium ranelate reduces nonvertebral fracture risk in postmenopausal osteoporosis.

    Related Health Concerns

    Study Details

    Year:2005
    Sample Size:5,091
    Duration:156 weeks
    Quality Score:8/10

    This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.