Allergen injection immunotherapy for seasonal allergic rhinitis
Calderon MA, Alves B, Jacobson M, Hurwitz B, Sheikh A, Durham S
Published in Cochrane Database of Systematic Reviews
Abstract
Cochrane systematic review assessing the clinical efficacy of subcutaneous allergen injection immunotherapy in seasonal allergic rhinitis.
Methodology
Meta-analysis of double-blind, placebo-controlled RCTs of subcutaneous allergen immunotherapy versus placebo.
Key Findings
Allergen injection immunotherapy produced a significant reduction in symptom scores and medication use compared with placebo.
Conclusions
Allergen injection immunotherapy is a highly effective treatment for seasonal allergic rhinitis and should be considered for refractory symptoms.
Limitations
Trials varied by allergen extract, dosing schedules, and outcome measures; risk of local and rare systemic adverse reactions.
Related Health Concerns
Study Details
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