meta_analysis
    2022

    Systematic Review and Meta-Analysis: Safety and Efficacy of Saccharomyces boulardii for Prevention of Clostridioides difficile Infection

    Tariq R, Tahir MW, Hayat M, Pardi DS, Khanna S

    Published in Journal of Gastrointestinal Infections

    Key Findings

    Pooled trials showed no statistically significant reduction in primary Clostridioides difficile infection with S. boulardii, and adverse events were comparable to control.

    Conclusions

    Evidence does not clearly support S. boulardii for preventing primary C. difficile infection.

    Limitations

    Few trials with low event rates; wide confidence intervals.

    Supplements Studied

    Pooled trials showed no statistically significant reduction in primary Clostridioides difficile infection with S. boulardii.

    Study Details

    Year:2022
    00
    Quality Score:6/10

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