meta_analysis
    2013
    High Quality

    Dietary nitrate supplementation and nitric oxide bioavailability: a systematic review and meta-analysis

    Siervo M, Lara J, Ogbonmwan I, Mathers JC

    Published in Journal of Nutrition

    Methodology

    Meta-analysis of randomized trials of inorganic nitrate and beetroot juice measuring plasma nitrite, nitrate and blood pressure.

    Key Findings

    Nitrate supplementation significantly raised plasma nitrite and lowered systolic blood pressure in a dose-dependent manner.

    Conclusions

    Dietary nitrate reliably increases nitric oxide bioavailability.

    Limitations

    Short interventions; effects on hard clinical outcomes untested.

    Outcomes Measured

    Nitric Oxide Production
    Primary

    Nitrate supplementation significantly raised plasma nitrite and lowered systolic blood pressure in a dose-dependent manner

    Study Details

    Year:2013
    Sample Size:254
    Duration:4 weeks
    Quality Score:8/10

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