meta_analysis
    2017
    High Quality

    Interventions for the management of radiotherapy-induced xerostomia and hyposalivation: a systematic review and meta-analysis

    Mercadante V, Al Hamad A, Lodi G, Porter S, Fedele S

    Published in Oral Oncology

    Key Findings

    Pilocarpine and acupuncture-like transcutaneous electrical nerve stimulation showed modest benefit; salivary substitutes showed little effect.

    Conclusions

    Muscarinic agonists remain the best-supported therapy for radiotherapy-induced xerostomia.

    Limitations

    Heterogeneous outcome measures, moderate risk of bias.

    Related Health Concerns

    Study Details

    Year:2017
    Quality Score:8/10

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