Omega-3 Polyunsaturated Fatty Acids in Youths with Attention Deficit Hyperactivity Disorder: A Systematic Review and Meta-Analysis of Clinical Trials and Biological Studies
Chang JP, Su KP, Mondelli V, Pariante CM
Published in Neuropsychopharmacology
Methodology
Systematic review and meta-analysis of 7 randomized controlled trials of omega-3 supplementation in youths with ADHD, plus biological studies of blood fatty acid levels
Key Findings
Omega-3 supplementation improved clinical symptoms of ADHD (SMD 0.38) and cognitive measures of attention (SMD 0.80 for omission errors); youths with ADHD had lower DHA, EPA and total omega-3 levels.
Conclusions
Omega-3 produces small-to-modest improvements in ADHD symptoms and attention, supporting adjunctive but not stand-alone use.
Limitations
Small trials, heterogeneous doses and outcome scales, short durations.
Supplements Studied
Omega-3 supplementation improved clinical symptoms and cognitive performances in children and adolescents with ADHD.
Related Health Concerns
Study Details
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Disclosures
Funding
UK Medical Research Council and academic sources
This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.