meta_analysis
    2018

    Intake of omega-3 polyunsaturated fatty acids in patients with rheumatoid arthritis: a systematic review and meta-analysis

    Gioxari A, Kaliora AC, Marantidou F

    Published in Nutrition

    Methodology

    Systematic review and meta-analysis of 20 RCTs of marine omega-3 in rheumatoid arthritis.

    Key Findings

    Omega-3 modestly reduced tender joint count, morning stiffness and NSAID use; effects on inflammatory markers were inconsistent.

    Conclusions

    Marine omega-3 is a reasonable adjunct for symptom control in rheumatoid arthritis, not a disease-modifying therapy.

    Limitations

    Small heterogeneous trials, varied doses and durations, open-label components.

    Supplements Studied

    Omega-3 modestly reduced tender joint count and NSAID use in rheumatoid arthritis.

    Outcomes Measured

    Autoimmune Modulation

    Omega-3 modestly improved rheumatoid arthritis symptom measures.

    Related Health Concerns

    Autoimmune Disease
    Rheumatoid Arthritis

    Study Details

    Year:2018
    Sample Size:1,000
    Quality Score:6/10

    Access Study

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