Outcome-specific efficacy of Lactobacillus plantarum in irritable bowel syndrome and functional gastrointestinal disorders: a systematic review of randomized trials
Liu Y, Yu X, Yu L, Tian F, Zhao J, Zhang H, Qian L, Wang Q, Xue Z, Zhai Q, Chen W
Published in Nutrients
Methodology
Systematic review of randomised controlled trials of Lactobacillus plantarum strains across gastrointestinal, metabolic and immune outcomes
Key Findings
Benefits were most consistent for IBS-related abdominal pain and bloating, while metabolic and lipid effects were small and strain-specific.
Conclusions
L. plantarum evidence is strongest for functional gut symptoms, weaker elsewhere.
Limitations
Strain heterogeneity; many small trials; publication bias likely.
Supplements Studied
Benefits were most consistent for IBS-related abdominal pain and bloating, while metabolic and lipid effects were small and strain-specific.
Outcomes Measured
Benefits were most consistent for IBS-related abdominal pain and bloating, while metabolic and lipid effects were small and strain-specific.
Study Details
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