Hawthorn (Crataegus spp.) in the treatment of cardiovascular disease: a review of pharmacology and clinical safety
Wang J, Xiong X, Feng B
Published in Evidence-Based Complementary and Alternative Medicine
Methodology
Review of pharmacological mechanisms and clinical safety data for Crataegus preparations in cardiovascular disease
Key Findings
Hawthorn flavonoids and oligomeric procyanidins exert positive inotropic, vasodilatory and antioxidant effects; adverse events in trials were mild, mainly dizziness and gastrointestinal upset.
Conclusions
Hawthorn has a plausible cardiovascular mechanism and a favourable short-term safety profile, but may interact with digoxin.
Limitations
Narrative synthesis; interaction data limited.
Supplements Studied
Adverse events in trials were mild, mainly dizziness and gastrointestinal upset.
Related Health Concerns
Study Details
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