Impact of chrysin on the molecular mechanisms underlying diabetic complications
Farkhondeh T, Samarghandian S, Roshanravan B
Published in Journal of Cellular Physiology
Methodology
Review of animal and cell studies of chrysin in diabetic neuropathy, nephropathy, retinopathy and cardiovascular complications
Key Findings
Chrysin reduced oxidative stress, inflammation and apoptosis in experimental models of diabetic complications.
Conclusions
Protective effects are consistent in animals, but clinical trials in patients with diabetes are still needed.
Limitations
No human data; publication bias toward positive animal findings.
Supplements Studied
The findings indicate that chrysin has protective effects against diabetes outcomes by modulating oxidative stress, inflammation, and apoptosis in animal models.
Study Details
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Disclosures
Funding
Not reported
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