rct
    2023
    High Quality

    Efficacy and Safety of Butylphthalide in Patients With Acute Ischemic Stroke: A Randomized Clinical Trial

    Wang A, et al

    Published in JAMA Neurol

    Key Findings

    Butylphthalide added to reperfusion therapy increased the proportion of patients with favourable 90-day functional outcome versus placebo.

    Conclusions

    Adjunct neuroprotection can improve outcomes after reperfusion therapy.

    Limitations

    Chinese population; mechanism on infarct volume inferred.

    Outcomes Measured

    Cerebral Infarction Volume

    NBP was associated with a higher proportion of patients achieving a favorable functional outcome at 90 days compared with placebo.

    Related Health Concerns

    Ischemic Stroke

    Study Details

    Year:2023
    Sample Size:1,216
    Duration:13 weeks
    Quality Score:8/10

    Access Study

    View on DOIView on PubMedOriginal Source

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