Effects of multivitamin supplement on cataract and age-related macular degeneration in a randomized trial of male physicians
Christen WG, Glynn RJ, Manson JE, MacFadyen J, Bubes V
Published in Ophthalmology
Methodology
Randomized double-blind placebo-controlled trial of a daily multivitamin over an average 11.2 years
Key Findings
Cataract incidence was modestly lower with multivitamin: 872 vs 945 cases, HR 0.91 (0.83-0.99, P=.04); no benefit for visually significant AMD
Conclusions
Long-term daily multivitamin use modestly reduced cataract risk in older men
Limitations
Male physicians only, self-reported endpoints, borderline effect size
Supplements Studied
These randomized trial data from a large cohort of middle-aged and older US male physicians indicate that long-term daily multivitamin use modestly and significantly decreased the risk of cataract.
Related Health Concerns
Study Details
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Disclosures
Funding
National Institutes of Health
This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.