meta_analysis
    2020
    High Quality

    Efficacy and safety of alginate formulations in patients with gastroesophageal reflux disease: a systematic review and meta-analysis of randomized controlled trials

    Zhao CX, Wang JW, Gong M

    Published in European Review for Medical and Pharmacological Sciences

    Methodology

    Meta-analysis of RCTs comparing alginate formulations with placebo, antacid or PPI for GERD, pooling symptom response and heartburn severity

    Key Findings

    Alginate formulations significantly improved GERD symptom response versus control with a favourable safety profile

    Conclusions

    Alginate is an effective and safe adjunct or alternative for symptomatic GERD

    Limitations

    Variable trial quality and formulations; potential publication bias; short follow-up

    Related Health Concerns

    GERD
    Heartburn & Acid Reflux

    Study Details

    Year:2020
    Quality Score:8/10

    Access Study

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