Effects of acetyl-L-carnitine and methylcobalamin for diabetic peripheral neuropathy: A multicenter, randomized, double-blind, controlled trial
Li S, Chen X, Li Q, Du J, Liu Z, Peng Y, Xu M, Xie J, Li Y, Yang H
Published in Journal of Diabetes Investigation
Key Findings
Acetyl-L-carnitine was non-inferior to methylcobalamin for symptom and nerve conduction improvement over 24 weeks, with good tolerability.
Conclusions
Acetyl-L-carnitine is as effective as vitamin B12 for diabetic peripheral neuropathy symptoms and nerve conduction.
Supplements Studied
ALC is as effective as MC in improving clinical symptoms and neurophysiological parameters for patients with diabetic peripheral neuropathy over a 24-week period with good tolerance.
Acetyl-L-carnitine was non-inferior to methylcobalamin for symptom and nerve conduction improvement over 24 weeks, with good tolerability.
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Study Details
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This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.